Christian Zierhut, PhD

Head of Laboratory

Christian obtained his undergraduate degree from the University of Vienna, where he studied meiotic DNA repair with Franz Klein.

  For his PhD, he worked with John Diffley at the CRUK Clare Hall Laboratories (now part of the Crick Institute). Here, Christian studied how DSBs are processed and activate the DNA damage response.

  Christian then did postdoctoral work with Hironori Funabiki at Rockefeller University. Here, he showed that chromatin is essential for the assembly of the nuclear envelope and the mitotic spindle. Subsequently, he showed that chromatin acts as a mark of self-DNA, preventing activation of self-sensing by cGAS.

  Christian joined the Cancer Biology Division of the ICR as a RadNet Fellow in 2020.